COLUMBUS, Ohio (Sports Network) - Terrelle Pryor threw for 247 yards and three touchdowns, as second-ranked Ohio State blew out Marshall, 45-7, in the season opener for both teams.
Pryor, coming off a sophomore season in which he led the Buckeyes to an 11-2 finish, including a Rose Bowl victory over Oregon, completed 17-of-25 passes.
Brandon Saine added 103 yards on the ground and two scores for Ohio State, which has won at least a share of the Big Ten title in each of the last five seasons. The Buckeyes rolled up 529 yards of offense.
Brian Rolle ran back an interception for a score for the Buckeyes (1-0), who will meet nationally-ranked Miami-Florida next Saturday.
"It was important that we come out and play hard and make some plays," Ohio State coach Jim Tressel said. "I think in Marshall's defense, a new staff coming in and playing against a solid team, that was a tough draw for them, but I thought we did some good things. It was important that we did, it would only be real important if we could learn that there weren't all good things and there's a whole bunch of things we have to do better if we have to compete at the next level next weekend."
Ahmed Shakoor scored on a return of a blocked field goal for Marshall (0-1), which played its first game under new head coach Doc Holliday. The Thundering Herd finished 7-6 last year, including a victory over Ohio in the Little Caesars Pizza Bowl.
Brian Anderson completed 17-of-28 passes for 135 yards for Marshall.
It was trouble right at the start for the Thundering Herd as Andre Booker had the ball stripped on the kickoff return. Nate Oliver came up with the ball for the Buckeyes at the 22. Just three plays later, Pryor threw to DeVier Posey on the left side of the end zone for a six-yard score.
"We stress not to put ball on ground and he hadn't done that, but it's unacceptable," Holliday said of Booker's fumble. "Any time you do that and you're playing Ohio State you don't have a chance. They are a great football team."
Saine broke off a 40-yard run, and then scored on the next play from four yards out on a sweep to the right side, for a 14-0 lead less than five minutes into the contest.
Drew Basil's 53-yard field goal later in the first was blocked and Shakoor raced the other way for the 61-yard score.
Ohio State needed less than a minute to respond as Pryor found Dane Sanzenbacher over the middle for a 65-yard bomb for a TD.
Saine scored on a 45-yard burst up the middle with less than four minutes remaining in the half.
On the second play after the ensuing kickoff, Anderson was picked off by Rolle, who raced 30 yards to the end zone for a dominating 35-7 spread with 2:46 left in the half.
The blowout continued as Pryor engineered the Buckeyes to another TD on the opening drive of the second half, this one an 11-yard connection to Posey.
Anderson led Marshall deep in OSU territory, but Martin Ward fumbled the ball away after making a catch, and the Buckeyes took over at their own six.
Devin Barclay kicked a 34-yard field goal in the fourth quarter.